Coagulation

Clinical and laboratory studies, in particular about use of low-molecular-weight heparin (LMWH) for patients with renal insufficiency, vitamin K antagonists (VKA), direct Xa inhibitors, and recombinant factor VIIa (rFVIIa).

Low-molecular-weight Heparins and Renal Insuffiency

Schmid P, Brodmann D, Fischer AG, Wuillemin WA
Prospective observational cohort study of bioaccumulation of dalteparin at a prophylactic dose in patients with peritoneal dialysis
J Thromb Haemost 2010;8(4):850-2
pharmacokinetics | PS and DB contributed equally to this study | registration | pubmed | text

Schmid P, Brodmann D, Odermatt Y, Fischer AG, Wuillemin WA
Study of bioaccumulation of dalteparin at a therapeutic dose in patients with renal insufficiency
J Thromb Haemost 2009;7(10):1629-32
pharmacokinetics | registration | pubmed | text

Schmid P, Fischer AG, Wuillemin WA
Low-molecular-weight heparin in patients with renal insufficiency
Swiss Med Wkly 2009;139(31-32):438-52
review | theme | calculators | pubmed | reply to a letter | text

Schmid P, Brodmann D, Fischer AG, Wuillemin WA
Study of bioaccumulation of dalteparin at a prophylactic dose in patients with various degrees of impaired renal function
J Thromb Haemost 2009;7(4):552-8
pharmacokinetics | registration | pubmed | text

Schmid P, Fischer AG, Wuillemin WA
Prevalence of impaired renal function in medical inpatients
Swiss Med Wkly 2007;137(35-36):514
epidemiological study | registration | pubmed | text

Vitamin K Antagonists

Nagler M, Bachmann LM, Schmid P, Raddatz-Müller P, Wuillemin WA
Patient self-management of oral anticoagulation with vitamin K antagonists in everyday practice: efficacy and safety in a nationwide long-term prospective cohort study
PLOS ONE 2014;9(4):e95761
clinical study | pubmed | software | text

Nagler M, Raddatz-Müller P, Schmid P, Bachmann LM, Wuillemin WA
Accuracy of the point-of-care coagulometer CoaguChek XS in the hands of patients
J Thromb Haemost 2013;11(1):197-9
clinical study | pubmed | text

Fritschi J, Raddatz-Müller P, Schmid P, Wuillemin WA
Patient self-management of long-term oral anticoagulation in Switzerland
Swiss Med Wkly 2007;137(17-18):252-8
clinical study | pubmed | software | text

Direct Xa Inhibitors

Studt JD, Alberio L, Angelillo-Scherrer A, Asmis LM, Fontana P, Korte W, Mendez A, Schmid P, Stricker H, Tsakiris DA, Wuillemin WA, Nagler M
Accuracy and consistency of anti-Xa activity measurement for determination of rivaroxaban plasma levels
J Thromb Haemost 2017;15(8):1576-83
pharmacokinetics | pubmed | text

Fontana P, Alberio L, Angelillo-Scherrer A, Asmis LM, Korte W, Mendez A, Schmid P, Stricker H, Studt JD, Tsakiris DA, Wuillemin WA, Nagler M
Impact of rivaroxaban on point-of-care assays
Thrombosis Research 2017;153:65-70
laboratory study | pubmed | text

rFVIIa

Colucci G, Helsing K, Demarmels Biasiutti F, Raio L, Schmid P, Tsakiris DA, Eberle B, Surbek D, Lämmle B, Alberio L
Standardized Management Protocol in Severe Postpartum Hemorrhage: A Single-Center Study
Clinical and Applied Thrombosis/Hemostasis 2018;24(6):884-93
clinical study | pubmed | text

Schmid P, Mordasini A, Luginbühl M, Regli B, Kohler HP, Zimmermann H, Inderbitzin D, Hirt A, Lämmle B, Alberio L
Low-dose recombinant factor VIIa for massive bleeding: A single centre observational cohort study with 73 patients
Swiss Med Wkly 2011;141:w13213
clinical study | pubmed | text